Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p033 | (1) | SRF2015

Functional evaluation of miRNAs during the ovarian follicular/luteal transition

Mohammed Bushra T , Duncan W Colin , Donadeu Francesc X

Little is known about the involvement of miRNAs in luteal development. Cattle provide a convenient model to study ovarian physiology in monovular species. Our previous microarray studies in bovine showed significant upregulation of miR-96 and miR-132 in luteal relative to follicular tissues. In the present study we used an in vitro model of forskolin-induced follicular granulosa cell luteinisation, transfection with specific locked nucleic acid inhibitors or mimics of...